Thermo Fisher Scientific hnRNP D Polyclonal Antibody
Western blot, IHC, ICC 등 다양한 응용에 적합한 hnRNP D 폴리클로날 항체. 사람, 마우스, 랫트 반응성. 합성 펩타이드 면역원으로 제작, 친화 크로마토그래피 정제. PBS/glycerol 완충액에 보관, -20°C 저장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HNRNPD (Accession Q14103), corresponding to amino acid residues G59–T109 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818088 |
Product Specific Information
Antibody detects endogenous levels of total hnRPD.
Target Information
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid-binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all hnRNPs are present in the nucleus, some shuttle between the nucleus and cytoplasm. The hnRNP proteins have distinct nucleic acid-binding properties. The protein encoded by this gene has two quasi-RRM domains that bind RNAs and localizes to both the nucleus and cytoplasm. It is implicated in the regulation of mRNA stability. Alternative splicing results in four transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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