Thermo Fisher Scientific Calcitonin Receptor Polyclonal Antibody
인간 Calcitonin Receptor를 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 6.8 µg/mL로 검증됨. 항원 친화 크로마토그래피로 정제된 액상형 항체이며 PBS 버퍼와 0.1% sodium azide 포함. 골 흡수 억제 및 형태형성 연구에 적합.
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Thermo Fisher Scientific Calcitonin Receptor Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 6.8 µg/mL
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from C-terminus of human Calcitonin Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550762 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Gibbon (100%)
- Monkey, Marmoset, Guinea pig (94%)
- Rabbit (88%)
- Mouse, Horse (81%)
Target Information
The Calcitonin Receptor inhibits bone resorption and is expressed during development, playing a role in morphogenesis.
Three alternatively spliced isoforms have been identified.
In addition to binding calcitonin, the receptor can complex with RAMP3 (receptor activity modifying protein) to bind amylin, which regulates pancreatic islet function and is involved in Type II diabetes.
Expression has been reported in artery, blood, bone, brain, kidney, lung, placenta, prostate, skeletal muscle, and thyroid.
ESTs have been isolated from bone, embryo, kidney, and melanocyte/uterus/fetal heart libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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