Thermo Fisher Scientific Calcitonin Receptor Polyclonal Antibody
Human Calcitonin Receptor를 인식하는 Rabbit Polyclonal 항체로, IHC(P) 적용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS buffer에 0.1% sodium azide 포함. 4°C 보관, 장기 보관 시 -20°C 권장. 연구용으로만 사용 가능.
- 카탈로그번호
- PA533379
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 9.2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from N-terminal extracellular domain of human Calcitonin Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550760 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human (100%)
- Gorilla, Marmoset (95%)
- Gibbon, Monkey (90%)
- Rabbit (85%)
- Panda, Dog, Horse (80%)
Target Information
The Calcitonin Receptor inhibits bone resorption and is expressed during development, playing a role in morphogenesis. Three alternatively spliced isoforms have been identified.
In addition to binding calcitonin, the receptor can complex with RAMP3 (receptor activity modifying protein) to bind amylin, which regulates pancreatic islet function and is involved in Type II diabetes.
Expression has been reported in artery, blood, bone, brain, kidney, lung, placenta, prostate, skeletal muscle, and thyroid. ESTs have been isolated from bone, embryo, kidney, and melanocyte/uterus/fetal heart libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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