Thermo Fisher Scientific Calcitonin Receptor Polyclonal Antibody
Rabbit polyclonal antibody targeting human Calcitonin Receptor for IHC (Paraffin) applications. Recognizes 17 amino acid peptide from the 2nd transmembrane domain. Unconjugated, liquid form, 0.25 mg/mL concentration. Stored at 2–8°C short term or -20°C...
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Thermo Fisher Scientific Calcitonin Receptor Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 9 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 17 amino acid peptide from 2nd transmembrane domain of human Calcitonin Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 1 month. For long term storage store at -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550761 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Monkey, Horse, Rabbit (100%)
Marmoset, Dog, Guinea pig (94%)
Target Information
The Calcitonin Receptor inhibits bone resorption and is expressed during development, playing a role in morphogenesis.
Three alternatively spliced isoforms have been identified.
In addition to binding calcitonin, the receptor can complex with RAMP3 (receptor activity modifying protein) to bind amylin, which regulates pancreatic islet function and is involved in Type II diabetes.
Reported expression in artery, blood, bone, brain, kidney, lung, placenta, prostate, skeletal muscle, and thyroid.
ESTs have been isolated from bone, embryo, kidney, and melanocyte/uterus/fetal heart libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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