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Thermo Fisher Scientific Geminin Polyclonal Antibody
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Thermo Fisher Scientific Geminin Polyclonal Antibody

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Geminin 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, IP 등 다양한 응용에 적합합니다. 인간 Geminin DNA 복제 억제 단백질의 C-말단 영역(160–209)을 면역원으로 사용했습니다. 액상 형태로 4°C 보관하며 연구용으로만 사용 가능합니다.

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Thermo Fisher Scientific · Thermo Fisher Scientific Geminin Polyclonal Antibody

Thermo Fisher Scientific Geminin Polyclonal Antibody

Applications and Tested Dilution

Application Tested Dilution
Western Blot (WB) 1:2,000–1:10,000
Immunohistochemistry (IHC) 1:1,000–1:5,000
Immunohistochemistry (Paraffin) (IHC (P)) 1:1,000–1:5,000
Immunoprecipitation (IP) 2–5 µg/mg lysate

Product Specifications

Specification Description
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Region between residue 160 and the C-terminus (residue 209) of human Geminin DNA replication inhibitor
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Storage Conditions 4°C
Shipping Conditions Wet ice

Product Specific Information

  • Recommended shelf life: 1 year from date of receipt
  • Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Target Information

GMNN inhibits DNA replication by preventing the incorporation of the MCM complex into the prereplication complex (pre-RC).
It is degraded during the mitotic phase of the cell cycle.
Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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