Thermo Fisher Scientific NKp44 Recombinant Rabbit Monoclonal Antibody (3F9Z5)
인간 NKp44(NCR2) 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot과 ELISA에 적합합니다. HEK293 세포에서 발현되며 Protein A로 정제되었습니다. 고농도(1.2 mg/mL) 액상 형태로 안정적이며, -20°C에서 보관합니다.
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Thermo Fisher Scientific NKp44 Recombinant Rabbit Monoclonal Antibody (3F9Z5)
Applications and Tested Dilutions
- Western Blot (WB): 1:500–1:1,000
- ELISA: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 3F9Z5 |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human NCTR2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Product Specific Information
Immunogen Sequence:
MAWRALHPLL LLLLLFPGSQ AQSKAQVLQS VAGQTLTVRC QYPPTGSLYE KKGWCKEASA LVCIRLVTSS KPRTMAWTSR FTIWDDPDAG FFTVTMTDLR
Target Information
CD336, also known as NKp44 or NCR2, is a 44-kDa transmembrane glycoprotein belonging to the natural cytotoxicity receptor (NCR) family. It contains an ITIM domain in the cytoplasmic tail and requires association with DAP12 for NK cell activation.
Originally thought to be expressed only on IL-2-activated NK cells and a subset of γδ T lymphocytes, CD336 has also been detected on IL-3-stimulated plasmacytoid dendritic cells, αβ T cells in the intestinal epithelium, and T cells in cord blood.
CD336 plays a key role in the innate immune response of activated NK cells against viral infections and tumor proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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