Thermo Fisher Scientific MST4 Recombinant Rabbit Monoclonal Antibody (4B9U7)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

4B9U7

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 317-416 of human MST4. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MST4,uniProtId:Q9P289-1,ncbiNodeId:9606,antigenRange:317-416,antigenLength:416,antigenImageFileName:MA5-55293_MST4_Q9P289-1_Rabbit.svg,antigenImageFileNamePDP:MA5-55293_MST4_Q9P289-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.8 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Product Specific Information

Immunogen Sequence: ENNTHPEWSF TTVRKKPDPK KVQNGAEQDL VQTLSCLSMI ITPAFAELKQ QDENNASRNQ AIEELEKSIA VAEAACPGIT DKMVKKLIEK FQKCSADESP

Target Information

MST4 is member of the Ste20-like kinase family of serine/threonine kinases and is overexpressed during prostate cancer development. The product of this gene is a member of the GCK group III family of kinases, which are a subset of the Ste20-like kinases. The encoded protein contains an amino-terminal kinase domain, and a carboxy-terminal regulatory domain that mediates homodimerization. The protein kinase localizes to the Golgi apparatus and is specifically activated by binding to the Golgi matrix protein GM130. It is also cleaved by caspase-3 in vitro, and may function in the apoptotic pathway. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.