Thermo Fisher Scientific Desmoglein 2 (DSG2) Recombinant Rabbit Monoclonal Antibody (8O0R6)
Thermo Fisher Scientific의 DSG2(Desmoglein 2) 재조합 토끼 단클론 항체(8O0R6)는 인간 시료에 반응하며, Western blot과 ELISA에 최적화되어 있습니다. HEK293 세포에서 발현된 IgG 형식의 항체로, 고순도의 친화 크로마토그래피 정제 제품입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 8O0R6 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1001–1118 of human Desmoglein 2 (Q14126) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.33 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911992 |
Product Specific Information
- Positive test controls include: HeLa, HepG2
- Immunogen sequence:
PLEGTQHLQD VPYVMVRERE SFLAPSSGVQ PTLAMPNIAV GQNVTVTERV LAPASTLQSS YQIPTENSMT ARNTTVSGAG VPGPLPDFGL EESGHSNSTI TTSSTRVTKH STVQHSYS
Target Information
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Three desmoglein subfamily members have been identified, all belonging to the cadherin cell adhesion molecule superfamily. These genes are clustered on chromosome 18. Desmoglein 2 has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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