Thermo Fisher Scientific Desmoglein 2 (DSG2) Recombinant Rabbit Monoclonal Antibody (8O0R6)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

8O0R6

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1001-1118 of human Desmoglein 2 (Q14126). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Desmoglein 2 (DSG2),uniProtId:Q14126-1,ncbiNodeId:9606,antigenRange:1001-1118,antigenLength:1118,antigenImageFileName:MA5-42851_Desmoglein_2_DSG2_Q14126-1_Rabbit.svg,antigenImageFileNamePDP:MA5-42851_Desmoglein_2_DSG2_Q14126-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.33 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2911992

Product Specific Information

Positive test controls include: HeLa, HepG2.

Immunogen sequence: PLEGTQHLQD VPYVMVRERE SFLAPSSGVQ PTLAMPNIAV GQNVTVTERV LAPASTLQSS YQIPTENSMT ARNTTVSGAG VPGPLPDFGL EESGHSNSTI TTSSTRVTKH STVQHSYS

Target Information

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.