Thermo Fisher Scientific PODXL Recombinant Rabbit Monoclonal Antibody (6S9A9)
PODXL 단백질을 표적하는 재조합 토끼 단클론 항체로, Western blot, IHC, ELISA에 적합합니다. 인간 시료에 반응하며 HEK293 세포에서 발현되었습니다. 고순도의 Affinity Chromatography 정제 항체로, 안정적인 PBS 기반 보존 용액에 포함되어 있습니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 6S9A9 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 300–479 of human PODXL (O00592) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911994 |
Product Specific Information
- Positive test controls: HCT116, 293T, U-251MG
- Immunogen sequence:
SPATALRTPT LPETMSSSPT AASTTHRYPK TPSPTVAHES NWAKCEDLET QTQSEKQLVL NLTGNTLCAG GASDEKLISL ICRAVKATFN PAQDKCGIRL ASVPGSQTVV VKEITIHTKL PAKDVYERLK DKWDELKEAG VSDMKLGDQG PPEEAEDRFS MPLIITIVCM ASFLLLVAAL
Target Information
This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane.
Other biological activities of the encoded protein include:
- Binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements
- Playing a role in hematopoietic cell differentiation
- Expression in vascular endothelium cells and binding to L-selectin
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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