Thermo Fisher Scientific HAT1 Recombinant Rabbit Monoclonal Antibody (7U2O3)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

7U2O3

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 200-400 of human KAT1/HAT1 (NP_0036332) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HAT1,uniProtId:O14929-1,ncbiNodeId:9606,antigenRange:200-400,antigenLength:419,antigenImageFileName:MA5-42850_HAT1_O14929-1_Rabbit.svg,antigenImageFileNamePDP:MA5-42850_HAT1_O14929-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.49 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2911991

Product Specific Information

Positive test controls include: MCF7, U-87MG, Mouse testis, Rat thymus. The target is usually found in the following locations: Cytoplasm, Nucleus, Nucleus matrix, nucleoplasm.

Immunogen sequence: HYFLVFEKYN KDGATLFATV GYMTVYNYYV YPDKTRPRVS QMLILTPFQG QGHGAQLLET VHRYYTEFPT VLDITAEDPS KSYVKLRDFV LVKLCQDLPC FSREKLMQGF NEDMVIEAQQ KFKINKQHAR RVYEILRLLV TDMSDAEQYR SYRLDIKRRL ISPYKKKQRD LAKMRKCLRP EELTNQMNQI EISMQHEQLE E

Target Information

The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.