Thermo Fisher Scientific HEY1 Monoclonal Antibody (4B3)
HEY1 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, ELISA에 적합합니다. Notch 신호전달 관련 연구에 유용하며, 고순도의 친화 크로마토그래피 정제 제품입니다. PBS(pH 7.4) 용액 상태로 제공되며, 보존제는 포함되지 않습니다.
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Applications
- ELISA (ELISA)
Tested Dilution: 0.1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4B3 |
| Immunogen | HEY1 (NP_036390, 121 a.a. ~ 220 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
DYRSLGFREC LAEVARYLSI IEGLDASDPL RVRLVSHLNN YASQREAASG AHAGLGHIPW GTVFGHHPHI AHPLLLPQNG HGNAGTTASP TEPHHQGRLG
Target Information
Hairy/enhancer-of-split related with YRPW motif protein 1 (HEY1) belongs to the HEY family and is a Notch Signaling Pathway Protein.
It contains one basic helix-loop-helix (bHLH) domain and one Orange domain. It is a downstream effector of Notch signaling which may be required for cardiovascular development.
HEY1 acts as a transcriptional repressor that binds preferentially to the canonical E-box sequence 5'-CACGTG-3'. It represses transcription by the cardiac transcriptional activators GATA4 and GATA6 and is also reported to be expressed during development of the nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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