Thermo Fisher Scientific HEY1 Monoclonal Antibody (1E10)
HEY1 단백질을 인식하는 Mouse IgG2a 단클론 항체로, Western blot 및 ELISA에 적합. Notch 신호 경로 관련 단백질 연구에 활용 가능. 고순도 친화 크로마토그래피 정제, PBS 기반 액상 형태로 제공.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.03 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1E10 |
| Immunogen | HEY1 (NP_036390, 121–220 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
DYRSLGFREC LAEVARYLSI IEGLDASDPL RVRLVSHLNN YASQREAASG AHAGLGHIPW GTVFGHHPHI AHPLLLPQNG HGNAGTTASP TEPHHQGRLG
Target Information
Hairy/enhancer-of-split related with YRPW motif protein 1 (HEY1) belongs to the HEY family and is a Notch Signaling Pathway protein.
It contains one basic helix-loop-helix (bHLH) domain and one Orange domain.
HEY1 acts as a transcriptional repressor binding preferentially to the canonical E-box sequence (5'-CACGTG-3').
It represses transcription by cardiac transcriptional activators GATA4 and GATA6 and is expressed during nervous system development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(해당 항체의 항원 관련 이미지: H00023462-M05_HEY1_Q9Y5J3-1_House_mouse.svg, H00023462-M05_HEY1_Q9Y5J3-1_House_mouse_PDP.jpeg)
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