Thermo Fisher Scientific HEY1 Monoclonal Antibody (1C9)
HEY1 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot 및 ELISA에 사용 가능. 인간 시료에 반응하며, Mouse IgG2a 동종형. 친화 크로마토그래피로 정제된 액상 형태로 제공되며, 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1C9 |
| Immunogen | HEY1 (NP_036390, 121–220 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
DYRSLGFREC LAEVARYLSI IEGLDASDPL RVRLVSHLNN YASQREAASG AHAGLGHIPW GTVFGHHPHI AHPLLLPQNG HGNAGTTASP TEPHHQGRLG
Target Information
Hairy/enhancer-of-split related with YRPW motif protein 1 (HEY1) belongs to the HEY family and is a Notch Signaling Pathway protein.
It contains one basic helix-loop-helix (bHLH) domain and one Orange domain.
HEY1 acts as a downstream effector of Notch signaling, potentially required for cardiovascular development.
It functions as a transcriptional repressor binding preferentially to the canonical E-box sequence 5'-CACGTG-3', and represses transcription by cardiac transcriptional activators GATA4 and GATA6.
HEY1 is also reported to be expressed during development of the nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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