Thermo Fisher Scientific SLC22A2 Monoclonal Antibody (CL0628)
인간 SLC22A2 단백질을 인식하는 마우스 단클론 항체로 IHC(P)에서 1:200–1:500 희석으로 사용 가능. 단백질 A로 정제된 액상형 항체이며, 4°C 단기 및 -20°C 장기 보관. 연구용으로 유기 양이온 수송체 연구에 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CL0628 |
| Immunogen | Recombinant protein corresponding to Human SLC22A2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.00 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637230 |
Product Specific Information
- Immunogen sequence:
ESPRWLISQN KNAEAMRIIK HIAKKNGKSL PASLQRLRLE EETGKKLNPS FLDLVRTPQI R - Epitope: Binds to an epitope within the peptide sequence KNAEAMRIIKHIAKK as determined by overlapping synthetic peptides.
- Ortholog identity: Mouse - 84%, Rat - 77%.
Target Information
Organic cation transporters (OCT) are expressed in the plasma membrane of epithelial cells from various tissues and play roles in eliminating endogenous amines, cationic drugs, and other xenobiotics.
OCTs have a 12-transmembrane-domain structure with a large extracellular hydrophilic loop.
- OCT1: Primarily expressed in the liver
- OCT2 (SLC22A2): Expressed in the kidney, localized to basolateral and luminal membranes of distal and proximal tubules; mediates pH-sensitive tubular uptake of organic compounds
- OCT3: Expressed in placenta, skeletal muscle, prostate, aorta, and liver
- OCT2-A: An additional splice variant of OCT2
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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