
Thermo Fisher Scientific Phospho-C-Jun (Ser73) Polyclonal Antibody
Phospho-C-Jun (Ser73) 폴리클로날 항체로 인간, 마우스, 랫, 제브라피쉬 반응성 보유. Western blot, IHC, ICC/IF에 적합. Ser73 인산화된 c-Jun 검출에 특이적. 고순도 정제 및 안정적 PBS/glycerol 저장용액 제공.
- 카탈로그번호
- PA5114562
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat, Zebrafish |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human JUN (Accession P05412), corresponding to amino acid residues around phosphorylated Ser73 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899198 |
Product Specific Information
This antibody detects endogenous levels of c-Jun only when phosphorylated at Serine 73.
Target Information
c-Jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'.
It promotes activity of NR5A1 when phosphorylated by HIPK3, leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
It is involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-114562_c-Jun_P05412-1_Rabbit.svg, PA5-114562_c-Jun_P05412-1_Rabbit_PDP.jpeg)
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