Thermo Fisher Scientific Phospho-TOP2A (Ser1525) Polyclonal Antibody
Phospho-TOP2A (Ser1525) 폴리클로날 항체로 인간, 생쥐, 랫드 시료에 반응. Western blot, IHC, ELISA에 적합. 항원 친화 크로마토그래피로 정제된 고순도 항체. DNA 합성 및 세포 분열 연구용으로 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | 1:100–1:300 |
| ELISA | 1:5,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human Topo IIα around the phosphorylation site of S1525 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.5% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609497 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
Topo IIα plays important roles in DNA synthesis and transcription, as well as chromosomal segregation during mitosis. It is a sensitive and specific marker of late S-, G2-, and M-phases in transformed and developmentally regulated normal cells. Topo IIα is also implicated in drug resistance of tumor cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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