Thermo Fisher Scientific Phospho-JNK1/JNK2/JNK3 (Tyr185) Polyclonal Antibody
Phospho-JNK1/JNK2/JNK3 (Tyr185) 항체로 인간, 마우스, 랫트 시료에 반응. Western blot, IHC, ELISA에 적합. 항원 친화 크로마토그래피로 정제된 Rabbit Polyclonal IgG. -20°C 보관, 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | 1:100–1:300 |
| ELISA | 1:20,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human JNK1/2/3 around the phosphorylation site of Y185 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.5% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608745 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
C-Jun N-terminal Kinase (JNK), also known as Mitogen-activated protein kinase (MAPK8), belongs to the MAPK superfamily of stress-activated protein kinases. MAPKs are serine-threonine protein kinases activated in response to various extracellular stimuli, mediating signal transduction from the cell surface to the nucleus.
JNK is involved in cellular processes such as proliferation, differentiation, transcription regulation, and development. JNK pathways are activated by stress and inflammatory signals. JNK is expressed as ten different isoforms due to differential mRNA splicing, with JNK1 and JNK2 being predominant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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