Thermo Fisher Scientific CD11c Monoclonal Antibody (N418), Alexa Fluor 532, eBioscience

Thermo Fisher Scientific CD11c Monoclonal Antibody (N418), Alexa Fluor 532, eBioscience

Applications and Tested Dilutions

Product Specifications

Available Formats

• Unconjugated
• Alexa Fluor 488
• Alexa Fluor 660
• Alexa Fluor 700
• APC
• APC-eFluor 780
• Biotin
• Brilliant UV series (395–805)
• Brilliant Violet series (421–711)
• eFluor series (450–660)
• FITC
• Functional Grade
• NovaFluor Blue & Yellow series
• PE and PE-Cyanine variants
• PerCP-Cyanine5.5
• Super Bright series (436–780)
• Request custom conjugation

Product Specific Information

The N418 monoclonal antibody reacts with mouse CD11c (integrin alpha X). CD11c associates with beta 2 integrin to form the CD11c/CD18 heterodimer, expressed by dendritic cells, intestinal intraepithelial lymphocytes, and some activated T cells. It binds to CD54, iC3b, and fibrinogen, contributing to leukocyte adhesion.

• Applications Reported: Flow cytometric analysis
• Applications Tested: Mouse splenocytes, ≤0.25 µg/test
• Recommended Use: Optimize antibody titration for best assay performance
• Fluorophore Info: Alexa Fluor® 532 (Excitation: 532 nm, Emission: 561 nm, Green laser compatible; not for 561 nm Yellow-Green laser)
• Recommended Filter: 560/14 band pass

Target Information

CD11 proteins (CD11a, CD11b, CD11c) form heterodimer adhesion molecules with CD18.

• CD11a: Expressed on B/T lymphocytes, macrophages, monocytes, neutrophils, basophils, eosinophils
• CD11b: Found in monocytes, macrophages, NK cells, some B/T cells, granulocytes
• CD11c: Found in monocytes, macrophages, NK cells, some granulocytes, subset of lymphocytes

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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