
Thermo Fisher Scientific CD31 Monoclonal Antibody (LCI-4), APC
APC 형광 표지된 CD31 단클론 항체로 인간 및 돼지 시료에 반응. FACS 분석에 적합하며 혈관 내피세포 표지용으로 사용. Lyophilized 형태로 보관 안정성이 우수하며 재구성 후 18개월까지 사용 가능.
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Thermo Fisher Scientific CD31 Monoclonal Antibody (LCI-4), APC
Applications
- Flow Cytometry (Flow)
Tested Dilution: Neat-1:10
Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Pig |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | LCI-4 |
| Immunogen | Porcine CD31/human IgGFc fusion protein |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Lyophilized |
| Concentration | Not Determined |
| Purification | Protein A |
| Storage Buffer | PBS with 1% BSA, 5% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE! |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538252 |
Additional Formats
Product Specific Information
- Reconstitute with 1 mL of distilled water.
- After reconstitution, store undiluted at 4ºC in the dark.
- Shelf life after reconstitution: approx. 18 months.
- For FACS analysis, use 10 µL of the suggested working dilution to label 1×10^6 cells in 100 µL.
- Mouse anti-Pig CD31, clone LCI-4 recognizes porcine CD31 (PECAM-1).
Target Information
CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling through ITIM motifs that recruit protein-tyrosine phosphatases upon phosphorylation.
CD31 is expressed throughout the vascular compartment, mainly at junctions between adjacent cells.
Its N-terminal Ig-like domain mediates homophilic binding, facilitating cell-cell interactions.
CD31 plays roles in:
- Integrin-mediated cell adhesion
- Transendothelial migration
- Angiogenesis
- Apoptosis
- Immunoreceptor signaling regulation
- Autoimmunity and thrombosis control
For Research Use Only. Not for use in diagnostic procedures. Not for resale without authorization.
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