Thermo Fisher Scientific CD31 Monoclonal Antibody (LCI-4), Biotin
CD31 단백질을 표적하는 Biotin 결합 단일클론 항체로, Flow Cytometry 분석에 적합합니다. 사람과 돼지 반응성이 있으며, LCI-4 클론 기반입니다. 단백질 A로 정제되어 높은 순도를 보장하며, 연구용으로만 사용 가능합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD31 Monoclonal Antibody (LCI-4), Biotin
Applications
Flow Cytometry (Flow)
- Tested Dilution: Neat–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Pig |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | LCI-4 |
| Immunogen | Porcine CD31/human IgGFc fusion protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538253 |
Additional Formats
Product Specific Information
For FACS analysis, use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.
Mouse anti-Pig CD31, clone LCI-4 recognizes porcine CD31, also known as Platelet Endothelial Cell Adhesion Molecule (PECAM-1).
Target Information
CD31 (Platelet Endothelial Cell Adhesion Molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling via dual ITIM motifs that, upon phosphorylation, provide docking sites for protein-tyrosine phosphatases.
CD31 is expressed ubiquitously within the vascular compartment, mainly at junctions between adjacent cells. The N-terminal Ig-like domain mediates homophilic binding, important for cell-cell interactions.
It plays diverse roles in:
- Integrin-mediated cell adhesion
- Transendothelial migration
- Angiogenesis
- Apoptosis
- Negative regulation of immunoreceptor signaling
- Autoimmunity and macrophage phagocytosis
- IgE-mediated anaphylaxis and thrombosis
CD31 is a key regulatory molecule in the vascular system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.