Thermo Fisher Scientific eIF2b epsilon Polyclonal Antibody
Thermo Fisher Scientific의 eIF2b epsilon Polyclonal Antibody는 인간 및 생쥐 시료에 반응하는 Rabbit IgG 항체로, WB, ICC/IF, ELISA, IP 등 다양한 응용에 적합합니다. 고순도 친화 크로마토그래피 정제 제품으로 안정적인 신호 검출을 제공합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5 µg–4 µg antibody for 200 µg–400 µg extracts |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 442–721 of human eIF2B epsilon (EIF2B5, NP_003898.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.19 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913650 |
Product Specific Information
Positive test controls include: U-87MG, A-549, HL-60, HT-1080, LO2, Mouse brain.
Immunogen sequence:
TLPEGSVISL HPPDAEEDED DGEFSDDSGA DQEKDKVKMK GYNPAEVGAA GKGYLWKAAG MNMEEEEELQ QNLWGLKINM EEESESESEQ SMDSEEPDSR GGSPQMDDIK VFQNEVLGTL QRGKEENISC DNLVLEINSL KYAYNISLKE VMQVLSHVVL EFPLQQMDSP LDSSRYCALL LPLLKAWSPV FRNYIKRAAD HLEALAAIED FFLEHEALGI SMAKVLMAFY QLEILAEETI LSWFSQRDTT DKGQQLRKNQ QLQRFIQWLK EAEEESSEDD
Target Information
This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (eIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis.
Mutations in this gene and other EIF2B subunit genes have been associated with leukoencephalopathy with vanishing white matter.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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