Thermo Fisher Scientific CABLES1 Polyclonal Antibody
CABLES1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 ELISA에 적합합니다. Human 및 Mouse 시료에 반응하며, 세포질과 핵에서 발현되는 타깃 단백질 검출에 유용합니다. Affinity Chromatography로 정제된 액상 항체입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–368 of human CABLES1 (NP_612384.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.84 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913656 |
Product Specific Information
- Positive test controls: MCF7, HT-29, A-549, HL-60, HeLa, Mouse brain
- Subcellular localization: Cytoplasm, Nucleus
Immunogen sequence:
MLSKRGCHAR IYADFPIRRL ISQRSSLETL EDIEENAPLR RCRTLSGSPR PKNFKKIHFI KNMRQHDTRN GRIVLISGRR SFCSIFSVLP YRDSTQVGDL KLDGGRQSTG AVSLKEIIGL EGVELGADGK TVSYTQFLLP TNAFGARRNT IDSTSSFSQF RNLSHRSLSI GRASGTQGSL DTGSDLGDFM DYDPNLLDDP QWPCGKHKRV LIFPSYMTTV IDYVKPSDLK KDMNETFKEK FPHIKLTLSK IRSLKREMRK LAQEDCGLEE PTVAMAFVYF EKLALKGKLN KQNRKLCAGA CVLLAAKIGS DLKKHEVKHL IDKLEEKFRL NRRELIAFEF PVLVALEFAL HLPEHEVMPH YRRLVQSS
Target Information
Cyclin-dependent kinase binding protein that enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases (e.g., CDK5 by ABL1 and CDK2 by WEE1).
- Promotes neuronal development and outgrowth
- Regulates p53/p73-induced cell death
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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