Thermo Fisher Scientific CABLES1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-368 of human CABLES1 (NP_612384.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CABLES1,uniProtId:Q8TDN4-1,ncbiNodeId:9606,antigenRange:1-368,antigenLength:633,antigenImageFileName:PA5-120084_CABLES1_Q8TDN4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120084_CABLES1_Q8TDN4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.84 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2913656

Product Specific Information

Positive test controls include: MCF7, HT-29, A-549, HL-60, HeLa, Mouse brain. The target is usually found in the following locations: Cytoplasm, Nucleus.

Immunogen sequence: MLSKRGCHAR IYADFPIRRL ISQRSSLETL EDIEENAPLR RCRTLSGSPR PKNFKKIHFI KNMRQHDTRN GRIVLISGRR SFCSIFSVLP YRDSTQVGDL KLDGGRQSTG AVSLKEIIGL EGVELGADGK TVSYTQFLLP TNAFGARRNT IDSTSSFSQF RNLSHRSLSI GRASGTQGSL DTGSDLGDFM DYDPNLLDDP QWPCGKHKRV LIFPSYMTTV IDYVKPSDLK KDMNETFKEK FPHIKLTLSK IRSLKREMRK LAQEDCGLEE PTVAMAFVYF EKLALKGKLN KQNRKLCAGA CVLLAAKIGS DLKKHEVKHL IDKLEEKFRL NRRELIAFEF PVLVALEFAL HLPEHEVMPH YRRLVQSS

Target Information

Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.