Thermo Fisher Scientific Carbonic Anhydrase I Polyclonal Antibody
Rabbit polyclonal antibody against human Carbonic Anhydrase I. Validated for WB and ELISA. Reacts with human and mouse samples. Supplied as liquid, affinity purified, 2.08 mg/mL in PBS with 50% glycerol. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein corresponding to amino acids 1–261 of human Carbonic Anhydrase I (CA1) (NP_001122303.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.08 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913653 |
Product Specific Information
- Positive test controls: 293T, Mouse liver, Mouse heart, Mouse brain
- Subcellular location: Cytoplasm
Immunogen sequence:
MASPDWGYDD KNGPEQWSKL YPIANGNNQS PVDIKTSETK HDTSLKPISV SYNPATAKEI INVGHSFHVN FEDNDNRSVL KGGPFSDSYR LFQFHFHWGS TNEHGSEHTV DGVKYSAELH VAHWNSAKYS SLAEAASKAD GLAVIGVLMK VGEANPKLQK VLDALQAIKT KGKRAPFTNF DPSTLLPSSL DFWTYPGSLT HPPLYESVTW IICKESISVS SEQLAQFRSL LSNVEGDNAV PMQHNNRPTQ PLKGRTVRAS F
Target Information
Carbonic anhydrases (CAs) are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They are involved in respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid.
CA1 encodes a cytosolic protein found primarily in erythrocytes and is closely linked to CA2 and CA3 genes on chromosome 8. Variants and alternatively spliced forms have been identified in various populations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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