Thermo Fisher Scientific H3.3 G34V oncohistone mutant Recombinant Rabbit Monoclonal Antibody (1H32L36), ChIP-Verified
H3.3 G34V 온코히스톤 변이체를 인식하는 재조합 토끼 단일클론 항체로, ChIP 검증 완료. Western blot 및 ChIP assay에 최적화. Expi293 발현, Protein A 정제, 0.5 mg/mL 농도. 인간 반응성, 원숭이 및 개구리 반응 예측.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:5,000 |
| ChIP assay (ChIP) | 1–5 µg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 1H32L36 |
| Immunogen | Peptides corresponding to human H3.3 G34V: (1) STGVVKKPH (2) STGRVKKPH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809244 |
Product Specific Information
This antibody is predicted to react with Monkey and Frog.
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of linker histone H1 with DNA between nucleosomes to form higher-order chromatin structures.
This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails and contain a palindromic termination element. The gene is located separately from other H3 genes clustered on chromosome 6p22–p21.3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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