
Thermo Fisher Scientific NPC2 Polyclonal Antibody
Thermo Fisher Scientific의 NPC2 Polyclonal Antibody는 인간, 마우스, 랫트 반응성을 가지며 Western Blot 및 IHC(P) 분석에 적합합니다. 항원 친화 크로마토그래피로 정제된 액상 형태의 비결합 항체로, Niemann-Pick C2 단백질 연구에 활용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 | – |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Dog |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NPC2. Recombinant protein control fragment (Product #RP-88996). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644765 |
Product Specific Information
Immunogen sequence:
PVQFKDCGSV DGVIKEVNVS PCPTQPCQLS KGQSYSVNVT FTSNIQSKSS KAVVHGILMG VPVPFPIPEP DGCKSGINCP IQKDKTYSYL NKLPVKSEYP SIKLVVEWQL QDDKNQSLFC WEIPVQIVSH
Highest antigen sequence identity to the following orthologs:
- Mouse: 81%
- Rat: 82%
Target Information
This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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