Thermo Fisher Scientific Amnionless Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Amnionless. Recombinant protein control fragment (Product #RP-88867). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Amnionless,uniProtId:Q9BXJ7-1,ncbiNodeId:9606,antigenRange:20-169,antigenLength:453,antigenImageFileName:PA5-51458_Amnionless_Q9BXJ7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51458_Amnionless_Q9BXJ7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2637913

Product Specific Information

Immunogen sequence: VSKLWVPNTD FDVAANWSQN RTPCAGGAVE FPADKMVSVL VQEGHAVSDM LLPLDGELVL ASGAGFGVSD VGSHLDCGAG EPAVFRDSDR FSWHDPHLWR SGDEAPGLFF VDAERVPCRH DDVFFPPSAS FRVGLGPGAS PVRVRSISAL

Highest antigen sequence identity to the following orthologs: Mouse - 69%, Rat - 67%.

Target Information

The protein encoded by this gene is a type I transmembrane protein. It is thought to modulate bone morphogenetic protein (BMP) receptor function by serving as an accessory or coreceptor, and thus facilitates or hinders BMP binding. It is known that the mouse AMN gene is expressed in the extraembryonic visceral endoderm layer during gastrulation, but it is found to be mutated in amnionless mouse. The encoded protein has sequence similarity to short gastrulation (Sog) and procollagen IIA proteins in Drosophila.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.