Thermo Fisher Scientific CDK11B Polyclonal Antibody
CDK11B 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 IHC(파라핀) 분석에 적합합니다. 인간, 생쥐, 랫트 시료에 반응하며, SDS-PAGE 기준 95% 이상 순도. 항원 친화 크로마토그래피로 정제된 액상 형태로 제공됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the N-terminus of human PITSLRE (CDK11B, UniProt ID: P21127-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2553397 |
Product Specific Information
- Detects endogenous protein at molecular weights of 110 and 92 kDa.
- Purity >95% by SDS-PAGE.
Target Information
The PITSLRE beta1 protein, a member of the Cdk family of protein kinases, induces apoptosis upon ectopic expression. Apoptosis is also induced by an amino-terminal deletion mutant retaining catalytic and carboxyterminal domains of PITSLRE beta1, but not by mutants lacking Histone H1 kinase activity or other Cdk family members.
The PITSLRE subfamily consists of ten isoforms (alpha, beta, gamma), named based on the conserved PSTAIRE box region of Cdc2 p34. Isoforms such as PITSLRE alpha1 (T cells) and PITSLRE beta1 (B cells and brain) show cell-type-specific expression, while others are ubiquitously expressed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(PA5-36154_CDK11B_P21127-1_Rabbit.svg 및 PA5-36154_CDK11B_P21127-1_Rabbit_PDP.jpeg)
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