Thermo Fisher Scientific TCF4/TCF12 Polyclonal Antibody
TCF4/TCF12 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. Human, Mouse, Rat에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 1 mg/mL 농도의 액상 형태로 제공되며, 연구용으로 사용됩니다.
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Thermo Fisher Scientific TCF4/TCF12 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 580–630 of human TCF-4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553395 |
Product Specific Information
- Detects endogenous protein at molecular weights of 60 and 72 kDa.
- Purity >95% by SDS-PAGE.
Target Information
T cell factors (TCFs) are a family of DNA-binding transcriptional activators essential for lymphoid cell development. These transcription factors are activated by Wnt-1 and Wingless pathways and contain a conserved high mobility group (HMG) box mediating DNA binding.
TCF-4 mainly localizes in the cytoplasm and is transported into the nucleus bound to beta-catenin. The TCF-4/beta-catenin complex induces expression of Wnt target genes, including multiple cancer-associated genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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