
Thermo Fisher Scientific IRF7 Recombinant Rabbit Monoclonal Antibody (1H31L43)
IRF7 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot에 최적화되어 있습니다. 높은 특이성과 재현성을 제공하며, 동물 유래 성분이 없는 포뮬레이션입니다. Protein A로 정제된 액상 형태이며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Thermo Fisher Scientific IRF7 Recombinant Rabbit Monoclonal Antibody (1H31L43)
Applications
- Western Blot (WB)
Tested Dilution: 1:250–1:1000
Publications: Refer to Thermo Fisher Scientific reference database.
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 1H31L43 |
| Immunogen | Recombinant protein corresponding to amino acids 269–378 of IRF7 (UniProt ID: Q92985-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2532301 |
Product Specific Information
Intact IgG appears on a non-reducing gel as a ~150 kDa band and upon reduction generates a ~25 kDa light chain band and a ~50 kDa heavy chain.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to rabbit immune repertoire
Target Information
Interferons (IFNs) are key modulators of immune interactions during viral infections, regulating innate and adaptive antiviral mechanisms.
IRF7 is a transcription factor involved in activation of virus-inducible cellular genes, including interferon beta chain genes. It plays a major role in innate immune pathways, interacting with TLR adaptor proteins (MyD88, Tirp/TRAM) and mediating TLR4 and TLR9 signaling.
There are at least four spliced isoforms of IRF7, though their functions remain unclear.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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