Thermo Fisher Scientific MCP-1 Polyclonal Antibody
Rat MCP-1 인식을 위한 Rabbit Polyclonal Antibody로, WB, IHC, ELISA, Functional Assay에 적합. Recombinant rat MCP-1 면역원 사용. 고순도 친화 크로마토그래피 정제, 동결건조 형태로 안정적 보관 가능. 연구용으로만 사용.
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Thermo Fisher Scientific MCP-1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.2 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent |
| ELISA | 0.5–2 µg/mL |
| Functional Assay | 4.0–6 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant rat MCP-1 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2071786 |
Product Specific Information
Reconstitute with 0.1 mL of distilled water. For long-term storage, the addition of 0.09% sodium azide is recommended.
Prior to reconstitution, store at 4ºC. After reconstitution, store undiluted at -20ºC, avoiding freeze/thaw cycles.
Rabbit anti-Rat MCP-1 antibody recognizes rat monocyte chemoattractant protein-1 (MCP-1), also known as CCL-2.
Rat MCP-1 is a chemokine of approximately 12 kDa, playing an important role in the inflammatory response of blood monocytes and tissue macrophages.
Target Information
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17.
Cytokines are secreted proteins involved in immunoregulatory and inflammatory processes.
The encoded protein is structurally related to the CXC subfamily of cytokines, characterized by two cysteines separated by a single amino acid.
This cytokine exhibits chemotactic activity for monocytes and basophils, but not for neutrophils or eosinophils.
It is implicated in diseases with monocytic infiltrates, such as psoriasis, rheumatoid arthritis, and atherosclerosis.
It binds to chemokine receptors CCR2 and CCR4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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