Thermo Fisher Scientific NCoR2 Polyclonal Antibody
NCoR2(SMRT) 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체입니다. Western blot, IHC, ICC/IF 등 다양한 응용에 사용 가능하며, Human 및 Mouse 시료에 반응합니다. 항원 친화 크로마토그래피로 정제된 고품질 연구용 항체입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 4 µg/mL | 7 publications |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:200 | - |
| Immunoprecipitation (IP) | - | 2 publications |
| ChIP assay (ChIP) | - | 4 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | His-tagged fusion protein corresponding to amino acid residues 95–565 from human SMRT |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2149135 |
Product Specific Information
PA1-843 detects silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) from human and mouse cells.
This antibody has been successfully used in Western blot, ICC/IF, and immunohistochemistry (paraffin) applications.
By Western blot, it detects an approximately 250 kDa protein representing SMRT from HeLa cell nuclear extracts.
The PA1-843 antigen is a His-tagged fusion protein corresponding to amino acid residues 95–565 from human SMRT.
Target Information
Steroid and thyroid hormones, as well as retinoic acid, regulate gene expression through intracellular receptor transcription factors belonging to the ligand-dependent nuclear receptor superfamily.
Coactivators and corepressors modulate transcriptional activity of these receptors.
Silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) and nuclear receptor corepressor (N-CoR) are related transcriptional corepressors containing domains that interact with unliganded nuclear receptors to repress their basal transcriptional activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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