Thermo Fisher Scientific CD9 Monoclonal Antibody (EM-04), APC

Thermo Fisher Scientific CD9 Monoclonal Antibody (EM-04), APC

Applications

• Flow Cytometry (Flow)

Tested Dilution: 2–3 µg/mL

Product Specifications

Additional Formats

• Unconjugated
• FITC
• PE
• Request custom conjugation

Product Specific Information

This antibody recognizes an extracellular epitope of CD9 antigen, a 24 kDa transmembrane protein expressed on platelets, monocytes, pre-B lymphocytes, granulocytes, and activated T lymphocytes.

Target Information

CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophils, stimulated T lymphocytes, and by neurons and glial cells in the peripheral nervous system.
CD9 belongs to the tetraspanin family, transversing the membrane four times. In pre-B cells and platelets, CD9 regulates cell activation and aggregation through association with integrin CD41/CD61 (GPIIb/GPIIIa).
It plays roles in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion. CD9 is essential for MHC II molecule association on dendritic cells, contributing to effective T cell stimulation.
CD9 expression is critical for suppression of cancer cell motility and metastasis and is considered a metastasis suppressor in solid tumors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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