Thermo Fisher Scientific CD9 Monoclonal Antibody (EM-04), APC
CD9 단백질의 세포 표면 발현을 검출하기 위한 Rat monoclonal antibody (Clone EM-04), APC 형광 표지. Flow cytometry에 적합하며 마우스 시료 반응성. 세포 활성 및 분화 연구용으로 적합. 액상 형태, 4°C 암소 보관.
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Thermo Fisher Scientific CD9 Monoclonal Antibody (EM-04), APC
Applications
- Flow Cytometry (Flow)
Tested Dilution: 2–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | EM-04 |
| Immunogen | Permeabilized murine bone marrow-derived mast cells (BMMC) |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152505 |
Additional Formats
- Unconjugated
- FITC
- PE
- Request custom conjugation
Product Specific Information
This antibody recognizes an extracellular epitope of CD9 antigen, a 24 kDa transmembrane protein expressed on platelets, monocytes, pre-B lymphocytes, granulocytes, and activated T lymphocytes.
Target Information
CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophils, stimulated T lymphocytes, and by neurons and glial cells in the peripheral nervous system.
CD9 belongs to the tetraspanin family, transversing the membrane four times. In pre-B cells and platelets, CD9 regulates cell activation and aggregation through association with integrin CD41/CD61 (GPIIb/GPIIIa).
It plays roles in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion. CD9 is essential for MHC II molecule association on dendritic cells, contributing to effective T cell stimulation.
CD9 expression is critical for suppression of cancer cell motility and metastasis and is considered a metastasis suppressor in solid tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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