Thermo Fisher Scientific TIGIT Recombinant Mouse Monoclonal Antibody (MBSA43), Alexa Fluor Plus 488

Thermo Fisher Scientific TIGIT Recombinant Mouse Monoclonal Antibody (MBSA43), Alexa Fluor Plus 488

Applications

• Flow Cytometry (Flow)

Tested Dilution: 0.25 µg/test
Publications: -

Product Specifications

Additional Formats

• Unconjugated
• Alexa Fluor Plus 555
• Alexa Fluor Plus 594
• Alexa Fluor Plus 647
• Request custom conjugation

Product Specific Information

Recombinant antibodies are produced using specific genes that code for the desired antibodies. These genes are cloned into an expression vector and expressed in vitro.
Advantages include improved specificity and consistent performance across lots.

Alexa Fluor™ Plus Antibody Benefits:

• Enhanced brightness compared to conventional Alexa Fluor dyes
• Improved signal-to-noise ratio for critical experiments
• Proprietary dye chemistry for superior imaging results

Usage Recommendations:

• Centrifuge conjugate solution briefly before use; apply supernatant only.
• Empirically determine appropriate dilution for optimal staining.
• Tested by flow cytometric analysis of human PBMCs (≤0.25 µg/test).
• Recommended cell number: 10⁵–10⁸ cells/test.
• Excitation: 494 nm; Emission: 519 nm; Laser: Blue Laser.

Target Information

TIGIT binds with high affinity to the poliovirus receptor (PVR), leading to increased IL10 secretion and decreased IL12B secretion, thereby suppressing T cell activation and promoting generation of mature immunoregulatory dendritic cells.

For Research Use Only. Not for use in diagnostic procedures or resale without authorization.

제품 이미지