Thermo Fisher Scientific CD127 Polyclonal Antibody
Thermo Fisher Scientific의 CD127 폴리클로날 항체는 인간 IL-7 수용체를 표적으로 하는 고품질 항체로, WB 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 버퍼에서 안정적으로 보관됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.01–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Interleukin 7 Receptor (amino acids 173–260 of the target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903728 |
Target Information
CD127 (Interleukin-7 receptor, IL-7R) is a glycoprotein involved in the regulation of lymphopoiesis. The activity of CD127 depends on the presence of the IL7R complex, which is composed of an alpha and a gamma chain. The gamma(c) chain also associates with the interleukin-2 receptor and mediates signal transduction, while the alpha chain determines specific signaling events through association with cytoplasmic signaling molecules.
CD127 promotes the proliferation of precursor B cells, thymocytes, T cell progenitors, and mature CD4+ and CD8+ T cells. Dysfunctions in CD127 are associated with severe combined immunodeficiency and T cell negative/B cell negative/NK positive severe combined immunodeficiency.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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