Thermo Fisher Scientific CD28 Monoclonal Antibody (CC220)
소 연구용 CD28 단일클론 항체(CC220)로, T 세포 공동자극 수용체 분석에 사용됩니다. Flow Cytometry 및 기능적 분석에 적합하며, Protein A로 정제된 액상 형태입니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
Functional Assay (Functional)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CC220 |
| Immunogen | Plasmid DNA encoding the bovine CD28 gene |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745305 |
Product Specific Information
Mouse anti-Bovine CD28, clone CC220 recognizes the bovine homologue of human CD28, a co-stimulatory cell surface molecule expressed by T cell subsets.
Target Information
CD28 antigen is a 44 kDa disulfide-linked homodimeric T cell-specific surface glycoprotein. It belongs to the immunoglobulin superfamily and is constitutively expressed on most peripheral blood T lymphocytes. CD28 provides the critical co-stimulatory signal to T cells by binding CD80 and CD86 on antigen-presenting cells, preventing anergic or apoptotic states. Expression patterns vary across thymic maturation stages, with highest levels on immature T cells. CD28 dysfunction is associated with diseases such as mycosis fungoides and Sezary’s Disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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