
Thermo Fisher Scientific INSRR Recombinant Rabbit Monoclonal Antibody (JM22-38)
INSRR 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 IHC(P)에서 검증됨. HEK293 세포 발현, Protein A 정제, 1 mg/mL 농도. 높은 특이성과 재현성을 제공하며 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JM22-38 |
| Immunogen | Synthetic peptide within Human Insulin Receptor R (aa 12–61) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2810008 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Specific antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal clones for production.
Advantages include:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to large rabbit immune repertoire
Target Information
INSRR (Insulin receptor-related receptor) is a member of the insulin receptor (IR) family. Although it does not bind insulin-like molecules, it exhibits tyrosine kinase activity similar to INSR.
It functions as a pH-sensing receptor activated by increased extracellular pH and triggers intracellular signaling involving IRS1 and AKT1/PKB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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