Thermo Fisher Scientific IL-2 Monoclonal Antibody, PeproTech

Applications

• Western Blot (WB): 0.25–0.50 µg/mL
• ELISA: 14.0–16.0 µg/mL

Product Specifications

Product Specific Information

AA Sequence of recombinant protein:
MAPTSSPAKE TQQHLEQLLL DLQVLLRGID NYKNLKLPMM LTFKFYLPKQ ATELKHLQCL ENELGALQRV LDLTQSKSFH LEDAGNFISN IRVTVVKLKG SENKFECQFD DEPATVVEFL RRWIAIAQSI ISTM.

Preparation:
Produced in BALB/c mice immunized with highly pure Recombinant Rat IL-2.
Anti-Rat IL-2-specific antibody was purified from cell culture by Protein G affinity chromatography.

Target Information

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that plays a key role in the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes, and macrophages.
IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is shared by IL-4 and IL-7.
Expression of the IL-2 gene in mature thymocytes is monoallelic, representing a unique regulatory mode for precise gene expression.
Disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease, indicating its essential role in immune response to antigenic stimuli.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.