Thermo Fisher Scientific IL-2 Monoclonal Antibody, PeproTech

Applications

Tested Dilution

Publications

Western Blot (WB)

2.0-4.0 µg/mL

-

ELISA (ELISA)

4.0-8.0 µg/mL

-

Miscellaneous PubMed (Misc)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Mouse

Published species

Mouse

Host/Isotype

Rat

Class

Monoclonal

Type

Antibody

Immunogen

E.coli-derived Recombinant Murine IL-2 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IL-2,uniProtId:P04351-1,ncbiNodeId:10090,antigenRange:22-169,antigenLength:169,antigenImageFileName:500-M127-500UG_IL-2_P04351-1_Rat.svg,antigenImageFileNamePDP:500-M127-500UG_IL-2_P04351-1_Rat_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Purification

Protein A

Storage buffer

PBS

Contains

no preservative

Storage conditions

-20°C

Shipping conditions

Ambient

RRID

AB_3074160

Product Specific Information

AA Sequence of recombinant protein: PTSSSTSSST AEAQQQQQQQ QQQQQHLEQL LMDLQELLSR MENYRNLKLP RMLTFKFYLP KQATELKDLQ CLEDELGPLR HVLDLTQSKS FQLEDAENFI SNIRVTVVKL KGSDNTFECQ FDDESATVVD FLRRWIAFCQ SIISTSPQ.

Preparation: Produced in Sprague Dawley rats immunized with highly pure Recombinant Murine IL-2. Anti-Murine IL-2-specific antibody was purified from cell culture by Protein A affinity chromatography.

Target Information

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.