Thermo Fisher Scientific IL-2 Monoclonal Antibody, PeproTech

Applications

Western Blot (WB)

• Tested Dilution: 2.0–4.0 µg/mL

ELISA

• Tested Dilution: 4.0–8.0 µg/mL

Miscellaneous (PubMed)

• Publications: View 1 publication

Product Specifications

Product Specific Information

AA Sequence of recombinant protein:
PTSSSTSSST AEAQQQQQQQ QQQQQHLEQL LMDLQELLSR MENYRNLKLP RMLTFKFYLP KQATELKDLQ CLEDELGPLR HVLDLTQSKS FQLEDAENFI SNIRVTVVKL KGSDNTFECQ FDDESATVVD FLRRWIAFCQ SIISTSPQ

Preparation:
Produced in Sprague Dawley rats immunized with highly pure Recombinant Murine IL-2.
Anti-Murine IL-2-specific antibody was purified from cell culture by Protein A affinity chromatography.

Target Information

Interleukin 2 (IL-2) is an immuno-modulatory cytokine essential for the proliferation of activated T cells, and differentiation of B cells, natural killer cells, monocytes, and macrophages.
IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is shared by IL-4 and IL-7.
Expression of the IL-2 gene in mature thymocytes is monoallelic, representing a unique regulatory mode for precise gene expression.
Disruption of an IL-2-like gene in mice results in an ulcerative colitis-like disease, highlighting its critical role in immune responses to antigenic stimuli.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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