Thermo Fisher Scientific METTL7A Polyclonal Antibody
METTL7A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot과 Immunocytochemistry에 적합하며, Human과 Mouse 시료에서 반응. 항원 친화 크로마토그래피로 정제된 액상 항체로, 연구용으로 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2 µg/mL |
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 13 amino acid peptide near the center of human MettL7A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153792 |
Product Specific Information
- Suggested positive control: MCF7 cell lysate
- PA5-20636 can be used with blocking peptide PEP-0756
Target Information
MettL7A belongs to the methyltransferase superfamily and is a probable methyltransferase.
Methyltransferases transfer methyl groups from donor to acceptor molecules, often modifying nucleic bases in DNA or amino acids in proteins.
DNA methylation is a key regulatory mechanism that can silence genes without altering the DNA sequence and is essential for normal mammalian development.
Disruption of methyltransferase genes can result in developmental defects or lethality.
Aberrant methylation patterns, such as silencing of tumor suppressor genes, have been implicated in tumorigenesis and metastasis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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