Thermo Fisher Scientific METTL7B Polyclonal Antibody
METTL7B 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western blot 및 IHC에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2–4 µg/mL |
| Immunohistochemistry (IHC) | 2.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid peptide near the carboxy terminus of human MettL7B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152960 |
Product Specific Information
- A suggested positive control is rat spleen tissue lysate.
- PA5-20637 can be used with blocking peptide PEP-0757.
Target Information
MettL7B belongs to the methyltransferase superfamily and is a probable methyltransferase. Methyltransferases transfer methyl groups from a donor to an acceptor, often on nucleic bases in DNA or amino acids in proteins. DNA methylation plays a role in gene regulation without altering the DNA sequence and is essential for normal embryonic development in mammals. Loss of DNA methyltransferase activity can lead to lethal phenotypes in mice. Aberrant methylation is also associated with cancer development through silencing of tumor suppressor genes, promoting tumorigenesis and metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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