Thermo Fisher Scientific GM2A Polyclonal Antibody
Human GM2A 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot 및 IHC(P) 검증 완료. 항원 친화 크로마토그래피 정제. PBS 기반 버퍼에 보존, 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GM2A. Recombinant protein control fragment (Product #RP-89941) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2789492 |
Product Specific Information
Immunogen sequence:
EPDPIIVPGN VTLSVMGSTS VPLSSPLKVD LVLEKEVAGL WIKIPCTDYI GSCTFEHFCD VLDMLIPTGE PCPEPLRTYG LPCHCPFKEG TYSLPKSEFV VPDLELPSWL TTGNYRIESV LSSSGKRLGC IKIAA
Target Information
This gene encodes a small glycolipid transport protein that acts as a substrate-specific cofactor for the lysosomal enzyme beta-hexosaminidase A. Together with GM2 ganglioside activator, it catalyzes the degradation of ganglioside GM2 and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene cause GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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