Thermo Fisher Scientific CD307e (FcRL5) Polyclonal Antibody
Human FcRL5 단백질을 표적으로 하는 Rabbit Polyclonal Antibody로, Western blot에 최적화되어 있습니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 1 mg/mL 농도로 제공됩니다. 연구용으로 B세포 발달 및 림프종 관련 연구에 적합합니다.
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 235–476 of Human FcRH5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547057 |
Product Specific Information
- Recommended positive controls: 293T, A431, Jurkat, Raji
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Fc receptor homologs (FcRH5), also known as IRTA2 proteins, are transmembrane proteins with sequence homology to classical Fc receptor families. FcRH5 functions as activating or inhibitory receptors on discrete B cell populations and are involved in B-cell development and differentiation in peripheral lymphoid organs.
FcRH5 expression is deregulated in multiple myeloma and Burkitt lymphoma cell lines with 1q21 abnormalities, suggesting a critical role in the pathogenesis of B-cell lymphoma.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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