Thermo Fisher Scientific AMPK gamma-1 Polyclonal Antibody
Rabbit polyclonal antibody against AMPK gamma-1 for Western blot applications. Reacts with human and non-human primate samples. Protein A purified, unconjugated form. Supplied in HEPES buffer with glycerol, stored at -20°C.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues near the amino terminus of human AMPK gamma-1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10978127 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit and non-catalytic beta and gamma subunits. It is an important energy-sensing enzyme that monitors cellular energy status.
In response to metabolic stress, AMPK is activated and phosphorylates acetyl-CoA carboxylase (ACC) and HMG-CoA reductase (HMGCR), key enzymes in fatty acid and cholesterol biosynthesis regulation.
This subunit represents one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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