Thermo Fisher Scientific Human TNPO3 Synthetic Peptide
인간 TNPO3 단백질의 N-말단 18개 아미노산 서열에 해당하는 합성 펩타이드로, PA5-20550 항체의 블로킹 펩타이드로 사용 가능. PBS(pH 7.2) 버퍼에 0.1% BSA 및 0.02% sodium azide 포함. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 18 amino acids near the amino terminus of human TNPO3.
PEP-0670 can be used as a blocking peptide with polyclonal antibody PA5-20550.
Target Information
TNPO3 is a member of the importin beta/transportin family of nuclear import receptors and is specific for the essential splicing factors termed SR proteins, binding specifically and directly to the arginine/serine (RS)-rich domains of these proteins. This interaction occurs only when the RS domains are phosphorylated. TNPO3 has been identified as an HIV dependency factor (HDF); depletion of TNPO3 inhibits HIV replication after reverse transcription but before integration, suggesting TNPO3 as a potential drug target in HIV treatment. At least three isoforms of TNPO3 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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