Thermo Fisher Scientific Human VPS53 Synthetic Peptide
인간 VPS53 단백질의 중심부 18개 아미노산 서열을 기반으로 한 합성 펩타이드입니다. 항체 차단용 블로킹 펩타이드로 사용 가능하며, 고순도 정제 상태로 PBS 버퍼에 보존됩니다. HIV 관련 연구 및 단백질 수송 메커니즘 연구에 적합합니다.
- 카탈로그번호
- PEP0669
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 18 amino acids near the center of human VPS53.
PEP-0669 can be used as a blocking peptide with polyclonal antibody PA5-20549.
Target Information
The sorting of acid hydrolases to lysosomes relies on mannose 6-phosphate receptors that cycle between the trans-Golgi network (TGN) and endosomes.
The maintenance of this cycle requires the function of the mammalian Golgi-associated retrograde protein (GARP) complex, composed of three subunits: VPS52, VPS53, and VPS54.
Depletion of any of these proteins impairs retrograde transport of multiple TGN proteins. VPS53 was identified as an HIV dependency factor (HDF) and plays a role in viral entry, suggesting its potential as a drug target in HIV treatment.
At least five isoforms of VPS53 are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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