Thermo Fisher Scientific Human SLC35D1 Synthetic Peptide
인간 SLC35D1 단백질의 카복시 말단 20개 아미노산 서열에 해당하는 합성 펩타이드입니다. 항체 PA5-20552의 블로킹 펩타이드로 사용 가능하며, UDP-당 운반체 연구에 활용됩니다. 정제된 액상 형태로 제공되며, PBS 버퍼에 0.1% BSA 및 sodium azide를 포함합니다.
- 카탈로그번호
- PEP0672
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human SLC35D1 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% Sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 20 amino acids near the carboxy terminus of human Slc35D1.
PEP-0672 can be used as a blocking peptide with polyclonal antibody PA5-20552.
Target Information
The solute carrier family Slc35 consists of at least 17 proteins that act as nucleotide sugar transporters localized to the Golgi apparatus and endoplasmic reticulum.
The ER-resident Slc family member Slc35D1 transports both UDP-glucuronic acid and UDP-N-acetylgalactosamine, substrates for chondroitin sulfate biosynthesis.
Mice lacking the Slc35D1 gene develop a lethal skeletal dysplasia with severe limb and facial shortening. Examination of epiphyseal cartilage shows a reduced proliferating zone, round chondrocytes, scarce matrices, and decreased proteoglycan aggregates.
Loss-of-function mutations in human Slc35D1 cause Schneckenbecken dysplasia, a severe skeletal disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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