Thermo Fisher Scientific VPS16 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 540-839 of human VPS16 (NP_0720972) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:VPS16,uniProtId:Q9H269-1,ncbiNodeId:9606,antigenRange:540-839,antigenLength:839,antigenImageFileName:PA5-90792_VPS16_Q9H269-1_Rabbit.svg,antigenImageFileNamePDP:PA5-90792_VPS16_Q9H269-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.52 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806239

Product Specific Information

Immunogen sequence: EYEPRSGEQV PLLLKMKRSK LALSKAIESG DTDLVFTVLL HLKNELNRGD FFMTLRNQPM ALSLYRQFCK HQELETLKDL YNQDDNHQEL GSFHIRASYA AEERIEGRVA ALQTAADAFY KAKNEFAAKA TEDQMRLLRL QRRLEDELGG QFLDLSLHDT VTTLILGGHN KRAEQLARDF RIPDKRLWWL KLTALADLED WEELEKFSKS KKSPIGYLPF VEICMKQHNK YEAKKYASRV GPEQKVKALL LVGDVAQAAD VAIEHRNEAE LSLVLSHCTG ATDGATADKI QRARAQAQKK; Positive Samples: A-549, Mouse brain, Mouse lung, Rat pancreas; Cellular Location: Cytoplasmic side, Cytoplasmic vesicle, Early endosome, Late endosome membrane, Lysosome membrane, Peripheral membrane protein, autophagosome, clathrin-coated vesicle

Target Information

Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps16 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.