Thermo Fisher Scientific VPS16 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Immunogen sequence:
EYEPRSGEQV PLLLKMKRSK LALSKAIESG DTDLVFTVLL HLKNELNRGD FFMTLRNQPM ALSLYRQFCK HQELETLKDL YNQDDNHQEL GSFHIRASYA AEERIEGRVA ALQTAADAFY KAKNEFAAKA TEDQMRLLRL QRRLEDELGG QFLDLSLHDT VTTLILGGHN KRAEQLARDF RIPDKRLWWL KLTALADLED WEELEKFSKS KKSPIGYLPF VEICMKQHNK YEAKKYASRV GPEQKVKALL LVGDVAQAAD VAIEHRNEAE LSLVLSHCTG ATDGATADKI QRARAQAQKK

Positive Samples:
A-549, Mouse brain, Mouse lung, Rat pancreas

Cellular Location:
Cytoplasmic side, Cytoplasmic vesicle, Early endosome, Late endosome membrane, Lysosome membrane, Peripheral membrane protein, autophagosome, clathrin-coated vesicle

Target Information

Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles.
This gene encodes the human homolog of yeast class C Vps16 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.
Two transcript variants encoding different isoforms have been found for this gene.
[provided by RefSeq, Jul 2009]

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.