Thermo Fisher Scientific MRPS35 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

Immunogen sequence:
MAAAALPAWL SLQSRARTLR AFSTAVYSAT PVPTPSLPER TPGNERPPRR KALPPRTEKM AVDQDWPSVY PVAAPFKPSA VPLPVRMGYP VKKGVPMAKE GNLELLKIPN FLHLTPVAIK KHCEALKDFC TEWPAALDSD EKCEKHFPIE IDSTDYVSSG PSVRNPRARV VVLRVKLSSL NLDDHAKKKL IKLVGERYCK TTDVLTIKTD RCPLRRQNYD YAVYLLTVLY HESWNTEEWE KSKTEADMEE YIWENSSSER NILETLLQMK AAEKNMEINK EELLGTKEIE EYKKSVVSLK NEEENENSIS QYKESVKRLL NVT

Positive Samples: HT-29, A-549, BxPC-3, A-375, Mouse heart, Mouse kidney, Mouse liver
Cellular Location: Mitochondrion

Target Information

Mammalian mitochondrial ribosomes (mitoribosomes) are responsible for protein synthesis within the mitochondrion. The mitoribosomes are composed of a 4:1 ratio of protein to RNA, with the proteins forming two subunits, the 28S and 39S subunits. Across species, the proteins that make up these subunits vary greatly in sequence, preventing easy recognition by sequence homology.

MRP-S35 (mitochondrial ribosomal protein S35), also known as MDS023, MRPS28, or HDCMD11P, is a 323 amino acid protein localized to the mitochondrion. It functions as a component of the 28S ribosomal subunit and mediates mitochondrial protein synthesis. The gene encoding MRP-S35 is located on human chromosome 10, which contains over 1,200 genes and represents approximately 4.5% of the human genome.

Safety Information

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.