
Thermo Fisher Scientific LOX Monoclonal Antibody (OTI6B11), TrueMAB
LOX 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, ICC/IF에 사용 가능. Human 반응성, 비결합형 형태로 동결건조 제공. 세포외 기질 형성과 암 전이 연구에 유용. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6B11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 22–168 of human LOX produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Lysyl oxidase (LOX) is a copper-containing amine oxidase that oxidizes primary amine substrates to reactive aldehydes. It plays a key role in extracellular matrix formation and repair. LOX also contributes to developmental regulation, tumor suppression, cell motility, and cellular senescence. The secreted form of LOX is linked to the invasive properties of hypoxic human cancer cells, making it an important therapeutic target for preventing and treating metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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