Thermo Fisher Scientific LOX Monoclonal Antibody (OTI6B7), TrueMAB
LOX 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, IHC, ICC, Flow cytometry에 적합. Human 시료에 반응하며, Lyophilized 형태로 제공. PBS buffer에 8% trehalose 포함, -20°C 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6B7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 22–168 of human LOX produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Lysyl oxidase (LOX) is a copper-containing amine oxidase involved in the oxidation of primary amine substrates to reactive aldehydes.
It plays a critical role in the formation and repair of the extracellular matrix and exhibits multifunctional biological roles, including developmental regulation, tumor suppression, cell motility, and cellular senescence.
The secreted form of LOX is associated with the invasive properties of hypoxic cancer cells and is a key factor in hypoxia-induced metastasis, making it a potential therapeutic target for metastasis prevention and treatment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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